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Both avian influenza (AI) and Newcastle disease (ND) viruses cause highly contagious respiratory diseases in chicken. These viruses are transmitted through the oro-faecal route, with airborne transmission via ...
Respiratory syndromes (RS) include a variety of diseases that lead to respiratory dysfunction, resulting in significant economic losses for the poultry industry. Infectious agents and unfavourable environmenta...
The development of effective poultry vaccines is crucial for maintaining flock health and productivity. In this study, we developed and evaluated a recombinant chimpanzee adenovirus vaccine (PAD-S1-HN) that si...
Streptococcus suis is a Gram-positive bacterium responsible for various infections in both pigs and humans. This study investigates the role of methionine acquisition in the growth and virulence of S. suis. The p...
Pullorum disease, caused by Salmonella pullorum (S. pullorum), is a highly contagious illness affecting the poultry industry. Emerging evidence suggests that Artemisia argyit essential oil can influence the compo...
Brucella is a successful pathogen that employs a plethora of immune evasion mechanisms. This contributes to pathogenesis and persistence and limits the efficacy of available treatments. An increasing understandin...
The host cell membrane-associated RING-CH8 protein (MARCH8) functions as an antiviral host factor by targeting viral envelope glycoproteins. Foot-and-mouth disease virus (FMDV) is a non-enveloped, positive-sen...
Respiratory viruses, including the influenza virus (IAV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), pose significant health threats. As tissue-resident macrophages, alveolar macrophages ...
Infection with Neospora caninum leads to reproductive failure in ruminants, such as cattle and goats; however, no effective vaccines or treatments are currently available to control this infection. Carefully regu...
Lumpy skin disease virus (LSDV) causes a severe emerging and transboundary disease in cattle. Infection with LSDV leads to the development of widespread dermal nodules. In addition to the skin, LSDV resides in...
Glaesserella parasuis cytolethal distending toxin (GpCDT) is a bacterial genotoxin whose main action is to activate DNA damage responses, induce cell cycle arrest, and induce the apoptosis of host cells. In our p...
The circulation of West Nile virus (WNV), Usutu virus (USUV), and tick-borne encephalitis virus (TBEV) was investigated in south-western France during the first six months of 2023, following the emergence of W...
A novel polyvalent broad-spectrum phage, vB_EcoM_XAM237 (XAM237), was isolated from pig farm sewage. It can simultaneously lyse multiple strains of pathogenic Escherichia coli (E. coli), demonstrating a broad hos...
Currently, there are no commercial serologic marker or differentiation of infected and vaccinated animal (DIVA) vaccines for the eradication of porcine reproductive and respiratory syndrome virus (PRRSV) infec...
Necrotic enteritis (NE) in broiler chickens is caused by the overgrowth of toxin-producing strains of Clostridium (C.) perfringens. This study aims to analyze the blood proteome of broiler chickens affected by NE...
African swine fever (ASF) is a highly contagious and severe hemorrhagic disease caused by African swine fever virus (ASFV). Currently, few safe and effective vaccines or antiviral drugs are available for its p...
Pseudorabies virus (PRV) causes neurological disorders and organ damage in diseased animals. After initial infection, PRV activity is gradually inhibited; however, stress stimulation increases the host’s gluco...
Effective mortality thresholds are critical for timely reporting and management of highly pathogenic avian influenza. Using standard modelling techniques, we evaluated the performance of different mortality th...
The pathogenesis of porcine epidemic diarrhea virus (PEDV) has not been fully clarified, which seriously hinders the prevention of the disease. The envelope (E) protein of PEDV induces the expression of pro-in...
The porcine reproductive and respiratory syndrome virus (PRRSV) has the highest mutation rate of any known RNA virus. The replication fidelity of RNA viruses can be modulated by subtle amino acid changes in th...
Streptococcus suis (S. suis) is an emerging zoonotic pathogen that threatens both animal and human health worldwide. UgpE is a protein subunit of the Ugp (uptake of glycerol phosphate) transporter system that is ...
Osseous echinococcosis causes severe “osteolytic” changes in the bone tissue of Echinococcus granulosus (E. granulosus) infection sites by promoting the over-differentiation of osteoclasts at the site. Nrf2 is a ...
Getah virus (GETV), a neglected and re-emerging mosquito-borne alphavirus, has become more serious and poses a potential threat to animal safety and public health. Given the lack of antivirals and vaccines aga...
Classical scrapie is a prion disease that affects goats and sheep and is transmitted mainly horizontally. However, infection can also occur vertically, from mother to offspring, but the exact mechanism is uncl...
Foot-and-mouth disease (FMD) is a highly contagious and transmissible disease that can have significant economic and trade repercussions during outbreaks. In Egypt, despite efforts to mitigate FMD through mand...
Airborne viruses spread rapidly in animal premises, which makes them difficult to contain. Electrostatic precipitators (ESP) are air cleaning devices that charge airborne particles and electrophoretically depo...
Foot-and-mouth disease (FMD) is a highly contagious disease affecting cloven-hoofed ungulates. This study aimed to enhance our understanding of the role of small ruminants and environmental contamination in th...
The H10 subtype of avian influenza virus (AIV) is widespread in poultry worldwide and poses a significant threat to animal health. With the emergence of sporadic and fatal cases in humans infected with H10 sub...
In 2010, rabbit hemorrhagic disease virus (RHDV) GI.2 emerged, and unlike RHDV GI.1, it caused mortality in young rabbits, while existing vaccines were not fully protective. The GI.2-specific monoclonal antibo...
Type II reference isolates of Toxoplasma gondii are widely used in animal toxoplasmosis models, but studies with Type III isolates remain scarce. In addition, these methods often rely on laboratory-adapted parasi...
Pseudorabies virus (PRV) infection leads to viral encephalitis and neurological damage in mice, causing significant neurological symptoms and brain damage. This study aimed to investigate the cellular mechanis...
Foot-and-mouth disease (FMD) severely restricts the healthy development of global animal husbandry, and the unclear pathogenic mechanism of FMD virus (FMDV) leads to difficulty in preventing and purifying FMD....
The retinoic acid-inducible gene I (RIG-I)-like receptors (RLRs) are major sensors against viral infection, but their roles in DNA virus infection largely remain unknown. This study found that a previously unc...
Escherichia coli is responsible for urinary tract infections (UTI) in humans and pets. This study aims to provide data on the virulome and resistome of E. coli strains isolated during bacteriuria in companion ani...
Rat hepatitis E virus (ratHEV-C1) is a newly zoonotic and globally distributed virus of increasing public health concern. Although rats of the genus Rattus are the main reservoir of this emerging virus, the role ...
Porcine epidemic diarrhea is an acute contagious disease caused by porcine epidemic diarrhea virus (PEDV), which severely constrains the development of the global swine industry. Host restriction factors const...
The original article was published in Veterinary Research 2024 55:124
Mycoplasma synoviae (M. synoviae) is a major bacterial pathogen that causes serious economic losses in the global poultry industry. Systemic changes in specific pathogen free White Leghorn egg-laying hens after M...
N6-methyladenosine (m6A) has attracted significant attention for its role in regulating the complex interaction between viruses and host cells. Porcine reproductive and respiratory syndrome virus (PRRSV) is a sig...
The apicomplexan parasite Eimeria is the causative agent of coccidiosis, which results in enteritis in animals and imposes a significant economic burden on the farming industry. Apicomplexan Apetala2/ERF (ApiAP2)...
Fowl adenovirus serotype 4 (FAdV-4) is a non-enveloped double-stranded DNA virus with a 43–45 kb genome. This characteristic makes it a promising viral vector for expressing other antigens in developing multi-...
The original article was published in Veterinary Research 2025 56:1
Listeriosis is a zoonotic disease caused by Listeria monocytogenes (Lm), posing a significant threat to the breeding industry and public health. Ruminant livestock are particularly susceptible to Lm, thus effect...
Bats are natural hosts for various highly pathogenic viruses, which pose a considerable threat to humans and animals. However, they rarely display signs of disease infection from these viruses. The expression ...
Many pathogens have the capacity to infect multiple hosts. Multi-species epidemiological systems are characterized by populations that interact and perform different functions in pathogen transmission and main...
Peste des petits ruminants (PPR), caused by the peste des petits ruminants virus (PPRV), is a highly contagious disease affecting ruminants. While goats and sheep are well-known hosts, PPRV has also spread to ...
H3N3 avian influenza viruses (AIVs) are less prevalent in poultry than H3N8 viruses. However, although relatively rare, reassortant H3N3 viruses have been known to appear in both domestic poultry and wild bird...
Cystic echinococcosis (CE) is a parasitic disease caused by the larval stage of Echinococcus granulosus, and the immunosuppressive microenvironment exacerbates disease progression. Ghrelin, a peptide hormone, pla...
Infection with novel duck reovirus (NDRV) results in severe splenic necrosis, leading to immunosuppression, secondary infections with other pathogens, and impairment of the immune effect of the vaccine. Howeve...
Listeriosis is a serious zoonotic disease caused by the genus Listeria, with Listeria monocytogenes being the most pathogenic species for humans and various animal species. This bacterium is commonly found in the...
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