Figure 8

Broad-spectrum antiviral activity of vidofludimus against SVA, EMCV, PEDV, and PRV. A Viability of BHK-21, Vero, and PK-15 cells pretreated with the indicated concentrations of Vi for 18 h, 16 h, and 20 h, respectively. Western blot and TCID50 were used to examine the inhibition activity of Vi against SVA (B and C), EMCV (D and E), PEDV F and G and PRV (H and I). Error bars represent the mean ± SD. *, P < 0.05; **, P < 0.01; ***, P < 0.001; ****, P < 0.0001; ns: not significant.