Table 2 Antibacterial activity of individual AMPs and antibiotics against PCN033 and RS218.
Antimicrobials | E. coli PCN033 | E. coli RS218 | ||
|---|---|---|---|---|
MIC (μM) | MBC (μM) | MIC (μM) | MBC (μM) | |
CATH-1 | 10 | 20 | 5 | 10 |
CATH-2 | 10 | 20 | 5 | 10 |
CATH-3 | 10 | 20 | 5 | 10 |
CATH-B1 | > 40 | > 40 | > 40 | > 40 |
CRAMP | 10 | 20 | 5 | 20 |
PAMP-36 | 2.5 | 10 | 2.5 | 5 |
PR-39 | 5 | 10 | 2.5 | 5 |
Streptomycin | 160 | 40,960 | 40,960 | > 40,960 |
Oxacillin | 5120 | 10,240 | 320 | 1280 |
Cefotaxime | < 0.625 | < 0.625 | < 0.625 | < 0.625 |
Tetracycline | 160 | 160 | 2.5 | 5 |
Gentamicin | 320 | 1280 | 2.5 | 5 |
Ampicillin | 20,480 | 40,960 | 5 | 10 |