Figure 6
Evolution of cellular immune responses over time. Means (± standard deviation) of counts of IFN-γ secreting cells in the six groups, obtained after either 272/20-H1avN1 (A) or 154/20-H1avN2 (B) stimulation of peripheral blood mononuclear cells (PBMC). The dates of the first and second challenges are indicated by a black and a green arrow, respectively. Significant differences between groups are indicated by different letters. H1N1 and H1N1 VACC: groups challenged at D0 with the 272/20-H1avN1 strain (HA clade 1C.2.1). H1N2 and H1N2 VACC: groups challenged at D0 with the 154/20-H1avN2 strain (HA clade 1C.2.4).