Figure 8

IFN-γ response detected by the IGRA (A-C) and the FCA (D-F) in calves experimentally infected with MAP (red) compared with the control group (blue). A corrected OD values after stimulation with PPDa; B corrected OD values after stimulation with PPDb; C Difference in OD values between PPDa- and PPDb-stimulated PBMC; D IFN-γ (MFI) in all CD4+ T cells, response to PPDj [x-fold vs. PPDp]; E IFN-γ (MFI) in all CD4+ T cells, response to WCSj; F IFN-γ (MFI) in all CD4+ T cells, response to WCSj [x-fold vs. WCSp].