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Table 3 Results of the cytokine/chemokines levels after BCoV infection between the intranasal and oral groups.

From: Evaluation of bovine coronavirus in Korean native calves challenged through different inoculation routes

Factors

Two-way RMANOVA

Post-hoc analysis

Infection time

Inoculation route

Interaction of variables

IFN-γ

0.222

0.611

0.392

 

IL-6

0.620

0.581

0.861

 

IL-10

0.039*

0.235

0.584

0.020*

IL-17A

0.691

0.943

0.341

 

IL-36RA

0.121

0.188

0.542

 

IL-8

0.000***

0.166

0.659

0.006**

IP-10

0.154

0.491

0.584

 

MCP-1

0.014*

0.167

0.501

0.024*

MIP-1β

0.044*

0.834

0.062

0.005**

VEGF-A

0.018*

0.517

0.712

 
  1. *p < 0.05, **p < 0.01, and ***p < 0.001.
  2. IFNγ: interferon gamma, IL: interleukin, IL-36RA: IL-36 receptor antagonist, IP-10 (CXCL10): IFNγ inducible protein 10, MCP-1 (CCL2): monocyte chemoattractant protein-1, MIP-1β (CCL4): macrophage inflammatory protein-1 beta, VEFG-A: vascular endothelial growth factor A.