Table 2 Global aquaculture fish vaccines development in the subfamily Alphairidovirinae
From: Fish Iridoviridae: infection, vaccination and immune response
Pathogen | Fish species | Vaccine type | Antigens | Delivery | Country | Protective effecta | References | |
|---|---|---|---|---|---|---|---|---|
Megalocytivirus | Â | |||||||
ISKNV | Mandarin fish | Inactivated | ORF099 | IP | China | Non-protective | [128] | |
| Â | Mandarin fish | Â | MCP, ORF054, ORF055, ORF101, ORF117, ORF125 | IP | China | High | [94] | |
| Â | Grouper | Â | WCIV | IP | China | High | [129] | |
| Â | Mandarin fish | Attenuated | ORF022L | IP | China | High | [130] | |
| Â | Nile tilapia | Subunit | MCP | IP | Thailand | b | [100] | |
| Â | Mandarin fish | Â | Helicase ORF086 | IP | China | High | [99] | |
| Â | Mandarin fish | Â | MCP | IMM | China | High | [102] | |
| Â | Mandarin fish | DNA | MCP | IMM | China | High | [101] | |
| Â | Chinese perch | Â | MCP | IM | China | High | [97] | |
| Â | Mandarin fish | Recombinant | MCP | IP | China | High | [106] | |
| Â | Largemouth bass | Recombinant live-vector | MCP (Baculovirus) | IP or IMM | China | High | [104] | |
| Â | Chinese perch | Â | Helicase (A. hydrophila) | IP | China | High | [131] | |
RSIV | Rock bream | Inactivated | WCIV | IP | China | Moderate | [88] | |
| Â | Red sea breamb Striped jackb | Â | WCIV WCIV | IP | Japan Japan | High | ||
| Â | Rock bream | Live | Rearing Temperature | IM | Republic of Korea | Moderate | [132] | |
| Â | Japanese flounder | DNA | MCP | IM | Japan | b | [133] | |
| Â | Rock bream | Â | Integrin | IP | Republic of Korea | b | [90] | |
| Â | Red sea bream | Â | MCP Transmembrane domain | IM | Japan | High | [91] | |
| Â | Red sea bream | Recombinant live-vector | ORF18R, ORF351R, MCP (E. coli) | IP | Japan | High | [89] | |
| Â | Red sea bream | Â | ORF380R (S. cerevisiae) | O | Japan | b | [134] | |
TGIV | Grouper | Recombinant | P2 (E. coli) | IMM | China | High | [135] | |
RBIV | Rock bream | Inactivated | WCIV | IP | Republic of Korea | High | [106] | |
| Â | Rock bream | DNA | Ankyrin | IM | Republic of Korea | Moderate | [109] | |
| Â | Rock bream | Â | MMP | IM | Republic of Korea | High | [108] | |
| Â | Turbot | Â | ORF75 | IM | China | High | [136] | |
| Â | Turbot | Â | P86 | IM | China | High | [137] | |
| Â | Rock bream | Recombinant live-vector | MCP (P. pastoris) | O | Republic of Korea | High | [138] | |
OMIV | Marbled sleepy goby | Inactivated | WCIV | IP | China | High | [111] | |
SDDV | Asian seabass | Inactivated | WCIV | IP | The Netherlands | High | [139] | |
| Â | Asian seabass | Recombinant Recombinant | MCP (E. coli) MCP (Baculovirus) | IP O | Thailand | b | [140] | |
Lymphocystivirus | Â | Â | Â | Â | Â | Â | Â | |
LCDV2 | Japanese flounder | Inactivated | WCIV | IP | Republic of Korea | b | [141] | |
| Â | Japanese flounder | DNA | MCP | IM, HD | China | High | [118] | |
| Â | Japanese flounder | DNA | MCP | O | China | High | ||
LCDV3 | Gilthead sea bream | DNA | MCP | IM | Spain | High | [67] | |
Ranavirus | Â | Â | Â | Â | Â | Â | Â | |
SGIV | Grouper | Inactivated | WCIV | IP | China | High | [119] | |
| Â | Grouper | DNA | ORF19R | IM | China | High | [121] | |
LMBV | Largemouth bass | Subunit | MCP | IMM | China | High | [142] | |
| Â | Largemouth bass | Recombinant live-vector | MCP (P. pastoris) | O | China | Moderate | [143] | |
| Â | Largemouth bass | Â | MCP (S. cerevisiae) | O | China | Moderate | [144] | |
| Â | Largemouth bass | Â | MCP (B. subtilis) | O | China | Moderate | [145] | |
| Â | Largemouth bass | DNA | MCP | HD | China | Moderate | [123] | |