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Figure 4 | Veterinary Research

Figure 4

From: Pasteurella multocida infection induces blood–brain barrier disruption by decreasing tight junctions and adherens junctions between neighbored brain microvascular endothelial cells

Figure 4

Pasteurella multocida infection induces the activation of NF-κB signaling in human brain microvascular endothelial cells (hBMECs). A–C Transcription of TNF-α (A), IL-6 (B), and IL-1β (C) in P. multocida infected cells compared to PBS-treated cells, as determined by qPCR. D Transcription of NF-κB in P. multocida infected cells compared to PBS-treated cells, as determined by qPCR. E Western blots demonstrating the expression of phosphorylated NF-κB P65 (p-P65) in P. multocida infected cells and PBS-treated cells. F Quantification of western blots demonstrating the expression of p-P65 in P. multocida infected cells and PBS-treated cells by ImageJ software. G Confocal laser scanning microscopy images showing the movement of NF-κB P65 into the cell nucleus in P. multocida infected cells and PBS-treated cells.

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Veterinary Research

ISSN: 1297-9716