Table 3 Data analysis of clinical signs was performed by the Chi-square test for each experimental comparison.

Ascites

LF-89|EM-90

8.71

3.43

1

1

0.003*

0.06

LF-89|Co-infection

16.70

n/a

1

n/a

 < 0.0001*

n/a

EM-90|Co-infection

8.71

3.43

1

1

0.003*

0.06

Swollen kidney

LF-89|EM-90

1.20

2.18

1

1

0.27

0.14

LF-89|Co-infection

13.60

1.04

1

1

0.0002*

0.31

EM-90|Co-infection

8.22

0.38

1

1

0.004*

0.54

Swollen spleen

LF-89|EM-90

6.17

n/a

1

n/a

0.01*

n/a

LF-89|Co-infection

8.71

1.04

1

1

0.003*

0.31

EM-90|Co-infection

0.38

1.04

1

1

0.54

0.31

Pale nodules in the liver

LF-89|EM-90

n/a

1.20

n/a

1

n/a

0.27

LF-89|Co-infection

9.88

0.00

1

1

0.002*

 > 0.99

EM-90|Co-infection

9.88

1.20

1

1

0.002*

0.27

Intestinal bleeding

LF-89|EM-90

1.04

1.20

1

1

0.31

0.27

LF-89|Co-infection

6.32

1.04

1

1

0.01*

0.31

EM-90|Co-infection

3.56

3.43

1

1

0.06

0.06

Distended ventricle

LF-89|EM-90

n/a

5.04

n/a

1

n/a

0.02*

LF-89|Co-infection

4.80

3.56

1

1

0.03*

0.06

EM-90|Co-infection

4.80

0.17

1

1

0.03*

0.68

Haemorrhage

LF-89|EM-90

0.68

2.27

1

1

0.41

0.1316

LF-89|Co-infection

6.17

1.20

1

1

0.01*

0.2733

EM-90|Co-infection

2.67

0.20

1

1

0.10

0.6534