Variation in the prion protein gene (PRNP) open reading frame sequence in French cervids

Table 3 Percentage of allele frequencies of PRNP polymorphisms in French red deer in 10 regions of France ( n = 998)

Codon	21		98		136		226		Δ_69-77
Amino acid variation	V	V	T	A	A	A	Q	E
Nucleotide sequence	GTC	GTT	ACC	GCC	GCT	GCC	CAG	GAG	Not present	present
Auvergne-Rhône-Alpes	99	1	62	38	46	54	46	54	100	0
Bourgogne-Franche-Comté	97	3	76	24	49	51	49	51	98	2
Bretagne	100	0	73	27	34	66	34	66	100	0
Centre-Val-de-Loire	100	0	85	15	20	80	20	80	100	0
Corse	100	0	75	25	26	74	26	74	100	0
Grand-Est	95	5	78	22	58	42	58	42	91	9
Hauts-de-France	96	4	67	33	47	53	48	52	86	14
Normandie	92	8	75	25	50	50	50	50	96	4
Nouvelle-Aquitaine	99	1	61	39	44	56	44	56	99	1
Occitanie	100	0	52	48	54	46	54	46	100	0
p-value	0.0001		0.0001		0.0001		0.0001		0.0001

The p values are based on the Fisher’s exact tests performed on the corresponding contingency tables.

ISSN: 1297-9716