Table 1 The VLPs vaccine of Picornavirus
From: Use of virus-like particles and nanoparticle-based vaccines for combating picornavirus infections
Virus | Composition | Expression system | Year of publication | Reference |
|---|---|---|---|---|
PV | cDNA | B/IC: Sf-9 | 1989 | [84] |
| Â | P1-3CD | Hela | 1991 | [83] |
| Â | P1-3CD | Saccharomyces cerevisiae | 1997 | [85] |
| Â | P1-3CD | Nicotiana benthamiana | 2017 | [86] |
| Â | P1-3CD | Pichia pastoris | 2020 | [87] |
| Â | P1-3CD | BHK-21 | 2021 | [89] |
| Â | P1, P2A peptide | Pichia pastoris | 2023 | [90] |
FMDV | cDNA | B/IC: Sf-9 | 1990 | [91] |
| Â | P1-2A, 3C | B/IC: Sf-9 | 2009 | [94] |
| Â | VP0/3/1 | Escherichia coli | 2009 | [97] |
| Â | P1-2A, 3C | B/IC: Sf-9 | 2013 | [95] |
| Â | P1-2A, 3C | B/IC: Sf-9 | 2013 | [96] |
| Â | VP0/3/1 | Escherichia coli | 2013 | [29] |
| Â | P1-2A, 3C | B/IC: Sf-21 | 2015 | [98] |
| Â | P1-2A, 3C | Samia cynthia ricini | 2016 | [99] |
| Â | P1-2A, 3C | Nicotiana benthamiana | 2018 | [100] |
| Â | P1-2A | Agrobacterium tumefaciens | 2018 | [101] |
| Â | VP0/3/1 | Escherichia coli | 2019 | [106] |
| Â | P1-2A, 3C | HEK-293A | 2020 | [102] |
| Â | P1-2A, 3C | HEK-2936E | 2020 | [103] |
| Â | VP0/3/1 | Escherichia coli | 2022 | [108] |
| Â | P1-2A, 3C | HEK-293Â T | 2022 | [104] |
| Â | P1-2A, 3C | BHK-21 | 2023 | [105] |
EV71 | P1-3CD | B/IC: Sf-9 | 2008 | [80] |
| Â | P1-3CD | Saccharomyces cerevisiae | 2013 | [112] |
| Â | P1-3CD | HEK-293A | 2015 | [113] |
| Â | P1, 3C | Flammulina velutipes | 2015 | [114] |
| Â | P1, 3C | Pichia pastoris | 2020 | [110] |
| Â | P1, 3CD | Pichia pastoris | 2023 | [192] |
SVA | VP0/3/1 | Escherichia coli | 2020 | [115] |
| Â | VP1-VP3, VP2-VP4 | B/IC: Sf-9 | 2024 | [117] |
EMCV | P1-2A, 3C | HEK-293FT | 2010 | [118] |
| Â | VP0/VP1/VP3 | Escherichia coli | 2024 | [193] |
CVA16 | P1-3CD | B/IC: Sf-9 | 2012 | [120] |
CVB3 | VP1/VP2/VP3/VP4 | B/IC: Sf-9 | 2012 | [121] |
DHAV | P1, 3CD | B/IC: Sf-9 | 2018 | [119] |