Figure 7

Passive protection against PEDV in piglets can be provided by colostrum from immunized sows. A Immunization procedures for sows and sample collection from piglets. Piglets born to sows immunized with the 17GXCZ-1ORF3d-P120 vaccine candidate and those born to unimmunized sows were infected with the PEDV strain. Serum samples were collected at 0, 2, 5, 9, 13 and 17 dpc to determine the levels of PEDV-N-protein-specific IgG (B) and PEDV-S-protein IgA (C) against the PEDV strain (*P < 0.05; **P < 0.01 and ***P < 0.001). Faecal scores (D) of the faeces after challenge with the PEDV strain. E Survival rates of piglets in the 17GXCZ-1ORF3d-P120/challenged control groups.