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Table 5 The influence of cc-CATH3, PD-CATH, and ML-CATH on the viability of mammalian cells under different concentrations

From: Bactericidal activities and biochemical features of 16 antimicrobial peptides against bovine-mastitis causative pathogens

Peptides

Concentration (μg/mL)

Cell viability ± SD (%)

PK15

HaCaT

cc-CATH3

64

91.1 ± 1.8

100.6 ± 0.4

 

160

32.7 ± 3.5

90.1 ± 4.8

ML-CATH

64

96.2 ± 0.4

99.7 ± 0.9

 

160

38.0 ± 2.2

98.0 ± 1.5

PD-CATH

64

43.6 ± 1.7

100.2 ± 0.2

 

160

7.4 ± 0.2

11.4 ± 0.5

Melittin

64

7.7 ± 0.2

7.2 ± 0.1

Triton X-100 (1%)a

13.3 ± 0.1

13.0 ± 0.4

  1. aA control for complete cell death.
  2. The experiment was repeated three times.
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Veterinary Research

ISSN: 1297-9716