Highlighted themes | Advances | Gaps and challenges |
---|---|---|
Avian Influenza Vaccines | • Virus-like particle vaccines demonstrated high immunogenicity and efficacy [7,8,9,10] • Regular updates to vaccines for antigenic matching to field viruses | • Control of Highly Pathogenic Avian Influenza (HPAI) • Current reliance on stamping out H5 and H7 outbreaks |
Bat immunology | • Understanding bat antiviral immunity and unique immunological traits [13] • Mechanisms of bats as viral reservoirs and their potential to prevent outbreaks | Understanding bat-host dynamics • Detailed molecular pathogenesis and disease reservoir mechanisms • Impact of dietary changes on antibody repertoire and viral immunity |
Porcine Disease Vaccines | • Innovative vaccine strategies for Streptococcus suis [11, 12] • Research on immunological responses to PRRS, ASF, and swine influenza | Efficacy of porcine vaccines • Absence of efficacy studies • Lack on basic research into germinal center disruption and IgG function |
Next-Generation Sequencing | • Advances in single-cell sequencing for identifying cell heterogeneity • Applications in autoimmunity, immuno-oncology, and vaccine development | • Specific training needed for young scientists based on LMIC and improve access to equipment |
Veterinary Vaccine Platforms | • Novel vaccine technologies for bacterial infections • Focus on deployment in low- and middle-income countries (LMICs) | • Affording accessible technologies for veterinary use |
Research development in Africa | • Limited veterinary professionals and infrastructure hindering growth • Lack of targeted investments to expand the veterinary industry | • Need for structured support in career development and growth • Enhanced funding and mentorship opportunities for young scientists |