Figure 7

Analysis of CD4+ and CD8+ T cells in the blood of experimental mice. A–H Changes in CD4+ and CD8+ T-cell levels on day 1, 3, 5, and 7 in mice in the oral IFNα/γ@PAMgel group and control group. I–J Ratios of CD4+ and CD8+ T cells. I CD4+ levels showed no difference after one day of oral administration between IFNα/γ@PAMgel and the PBS control groups but showed a significant difference 3 to 7 days after administration. (*p < 0.05; ***p < 0.001; ns, not significant). J There was a significant increase in the ratio of CD8+ T cells in the IFNα/γ@PAM.gel group compared with that in the control group from 1 to 7 days. (**p < 0.01; ***p < 0.001).