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Table 2 Description of the genetic markers associated with survival up to 105 days after the PRRS outbreak depending on piglet genotype

From: Insights into genetic determinants of piglet survival during a PRRSV outbreak

Assay name

Allele (frequency)

Genotype (survival up to 105 days)3

Gene

Resistant

Susceptible

LRT1

Homozygous resistant

Heterozygous

Homozygous susceptible

rs1107556229

CD163

A (0.58)

G (0.42)

5.88 *

AA (0.74)

AG (0.68)

GG (0.42)

rs340943904

GBP5

T (0.20)

G (0.80)

4.01 *

TT (1.00)

GT (0.70)

GG (0.58)

MX1_c.−547ins + 250

MX1

D (0.78)

I (0.22)

2.02 ns

DD (0.68)

ID (0.55)

II (0.59)

rs695254451

MMRN1

T (0.29)

C (0.71)

2.57 ns

TT (0.72)

TC (0.67)

CC (0.58)

rs3415953402

CRP

A (0.93)

C (0.07)

0.66 ns

AA (0.68)

AC (0.56)

 
  1. 1P-value for the likelihood ratio test of proportional hazard models including or not each SNP: *** = P < 0.001, ** = 0.001 < P < 0.01, * = 0.01 < P < 0.05, +  = 0.05 < P < 0.10, ns = P > 0.10
  2. 2CRP polymorphisms (rs341595340 and rs327446000) were found to be in complete LD with each other
  3. 3Predicted proportion of animal still alive at 105 days depending on their genotype for each SNP: animals with two resistant alleles (Homozygous resistant), animals with one resistant and one susceptible allele (Heterozygous), and animals with two susceptible alleles (Homozygous susceptible)
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Veterinary Research

ISSN: 1297-9716