Figure 5
From: Revealing novel and conservative CD8+T-cell epitopes with MHC B2 restriction on ALV-J
Conservation of the sequences of three identified T-cell epitopes among ALV strains of various subtypes. A total of 205 pol protein sequences and 256 gag protein sequences of avian leukosis virus (ALV-A, ALV-B, ALV-E, ALV-J, and ALV-K) reported from 2001–2024 in the NCBI database were used. Peptide sequences were aligned using the ClustalW algorithm of the MEGA7.0 software. The frequency of mutation was determined (A, B, and C). The peptide sequences of ALV are represented by various colored bars. The numbers above the bars indicate the proportion of virus strains and the mutated amino acids are marked in red.