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Figure 3 | Veterinary Research

Figure 3

From: PRV-1b and PRV-3a infection is associated with the same clinical disease in coho salmon (Oncorhynchus kisutch) farmed in Chile: unraveling the pathogenesis of the orthoreoviral cardiomyopathy and hemolytic jaundice (OCHJ)

Figure 3

Main macroscopic pathology findings in PRV-1b and PRV-3a infected coho salmon associated with clinical disease characterized by anemia and jaundice. Ruptured heart, pale heart, hemopericardium and clot in pericardial cavity, mottled liver and jaundice in peri-visceral fat in a specimen infected with A PRV-1b, and B infected with PRV-3a. C Pale heart and clot in abdominal cavity over liver and viscera in a specimen infected with PRV-1b. D Nutmeg liver with biliary colectasis and plethoric gallbladder in a fish infected with PRV-3a. E Clot removed from pericardial cavity, mottled liver and ascites in fish infected with PRV-1b. F Clot in pericardial cavity completely covering the heart, mottled liver and abundant jaundice in peri-visceral fat and parietal peritoneum in fish infected with PRV-3a. The macroscopic manifestation of hemopericardium is evidenced by the presence of a clot in the pericardial cavity probably induced by atrial rupture. The “mottled” appearance of the liver with green and brown spots on the surface and plethoric gallbladder is associated with biliary cholestasis. The first lesions seem to appear in the heart and then in the liver and jaundice.

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