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Table 1 Characteristics of experimental animals

From: Pathogen delivery route impacts disease severity in experimental Mycoplasma ovipneumoniae infection of domestic lambs

Experimental group

N

Treatment

Route

Males

Litter size

Weight at start (kg)

Age at start (d)

Control

2

PBS

URT

3

2.2 ± 0.4

27.7 ± 9.1

64.0 ± 11.1

3

PBS

LRT

URT1

5 (4)3

Nasal wash

URT

3

1.6 ± 0.5

28.5 ± 4.5

59.8 ± 7.2

LRT2

5

Nasal wash

LRT

3

1.6 ± 0.9

31.2 ± 6.5

67.2 ± 8.6

P value

   

 > 0.99

0.288

0.709

0.460

  1. 1Inoculation of upper respiratory tract via nasal, conjunctival, and oral mucosae.
  2. 2Inoculation of lower respiratory tract via endoscope.
  3. 3One lamb was euthanized prior to the experimental endpoint due to urinary tract disease. Groups were compared using one-way ANOVA with Tukey’s multiple comparisons test.