Table 2 Scoring criteria for histopathological assessment of lung tissues, based on Passmore 2018, Respiratory Research [32]
Score | Pulmonary edema and congestion | Alveolar and interstitial inflammation | Bronchiolar inflammation | BALT hyperplasia |
|---|---|---|---|---|
0 | Minimal/Normal | Minimal/Absent | Minimal/Normal | None |
1 | Mild edema and/or congestion | Mild inflammatory exudate | Mild infiltration of inflammatory cells | Mild |
2 | Moderate edema and/or congestion | Moderate inflammatory exudate | Moderate infiltration of inflammatory cells | Moderate |
3 | Severe edema and congestion ± intra-alveolar hemorrhage | Marked-severe inflammatory exudate | Marked/severe infiltration by inflammatory cells, ± epithelial damage | Marked |