Figure 11

Comparison of CSF Nf-L levels between healthy cattle and those (age, 2–12 months) with a CNS metabolic/toxic disorder (A) and vitamin B1 deficiency (B). (A) There was no substantial difference in CSF Nf-L concentration between healthy calves and those with a metabolic/toxic disorder. B CSF Nf-L levels were significantly higher in calves with a vitamin B1 deficiency. The median, IQR, maximum and minimum are shown. The Mann–Whitney test was applied. Asterisks (*) denote the level of statistical significance: * p < 0.05. ns denotes not significant. CSF cerebrospinal fluid, CNS central nervous system, IQR interquartile range, Nf-L neurofilament light chain