Figure 8

Comparison of CSF Nf-L levels between healthy calves and those (age, < 2 months) with a CNS infectious/inflammatory disorder (A) and E. coli CNS infection (B). CSF Nf-L levels were significantly higher in calves with an infectious/inflammatory disorder (A). CSF Nf-L levels were significantly higher in calves with an E. coli infection (B). The median, IQR, maximum and minimum are shown. The Mann–Whitney test was used. Asterisks (*) denote the level of statistical significance: * p < 0.05, **** p < 0.0001. CSF denotes cerebrospinal fluid, CNS central nervous system, IQR interquartile range, Nf-L neurofilament light chain.