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Figure 4 | Veterinary Research

Figure 4

From: MyD88 inhibitor TJ-M2010-5 alleviates spleen impairment and inflammation by inhibiting the PI3K/miR-136-5p/AKT3 pathway in the early infection of Trichinella spiralis

Figure 4

Global view of miRNAs expression profiles in mice spleens during the early infection of T. spiralis. A: Schematic diagram illustrating the experimental protocols. B: Venn diagram showing the intersection of the DEmiRNAs among 5 d group vs 0 d group and TJ5_5 d group. C: mRNA expression of DEmiRNAs in different groups (0, 5 and TJ5_5 d groups) by qPCR. Compared with 0 d group: * P < 0.05, ** P < 0.01, *** P < 0.001. Compared with TJ5_5 d group: # P < 0.05, ## P < 0.01, ### P < 0.001. D: Volcano plots of DEmiRNAs in 5 d group vs 0 d group (A) and TJ5_5d group (B). Red, higher-expressed miRNAs; Blue, lower-expressed miRNAs. E–F: GO (E) and KEGG (F) pathway analysis for DEmiRNAs.

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Veterinary Research

ISSN: 1297-9716